Potential antidepressant compound NSI-189

  • Nsi-189 (free base & phosphate)


  • NSI-189 phosphate
  • UNII-HX0VO60T62
  • 1270138-41-4
  • HX0VO60T62
  • NSI 189 Phosphate

NSI-189 is an antidepressant and neurogenic chemical that may be able to improve cognitive function, treat traumatic brain injury, Alzheimer’s Disease (AD), Post-Traumatic Stress Disorder (PTSD), and stroke, and prevent cognitive and memory decline in aging

Technical Data for NSI-189

M. Wt366.5
StorageStore at +4°C
Purity≥99% (HPLC)
CAS Number1270138-40-3 (Free base);1270138-41-4 (Phosphate)
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Many expirements suggest that NSI-189 is effective as a safe adjunctive therapy, with most compelling antidepressant and procognitive benefits noted in patients with moderate depression.

Main Benefit  as follows

  •  Improve Depression
  •  Improvde Cognition
  • Help with Stroke
  • Help with Diabetes


Solubility (25℃)

  1. DMSO  73mg/ml
  2. Ethanol 73mg/ml
  3. Water insoluble




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