Pyrilutamide KX-826 for the potential treatment of androgenetic alopecia in males and females
KX-826 is a nonsteroidal antiandrogen (NSAA) – specifically, a selective high-affinity silent antagonist of the androgen receptor (AR) – which is under development by Suzhou Kintor Pharmaceuticals, inc., a subsidiary of Kintor Pharmaceutical Limited
Technical Data for KX-826
| M. Wt | 482.43 |
| Formula | C21H15F5N4O2S |
| Storage | Store at +4°C |
| Purity | ≥99% (HPLC) |
| CAS Number | 1272719-00-2 |
| Drug Class | Nonsteroidal antiandrogen |
| Other name | Pyrilutamide; KX-826 |
Pharmacodynamics | Pyrilutamide binds to the androgen receptor with a very high affinity with an IC50 of 0.28nM. Reference drug Bicalutamide had an IC50 of 3.1nM |
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