Bimatoprost for eyelash growth

Bimatoprost is a prostaglandin analog/prodrug used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. It reduces intraocular pressure (IOP) by increasing the outflow of aqueous fluid from the eyes. It has also been used and prescribed off-label to lengthen eyelashes

Technical Data for Bimatoprost

M. Wt415.57
FormulaC25H37NO4
StorageStore at +4°C
Purity≥99% (HPLC)
CAS Number155206-00-1
EINECS642-890-9
AppearancePowder Form
Smiles

CCNC(=O)CCCC=CCC1C(CC(C1C=CC(CCC2=CC=CC=C2)O)O)O

Bimatoprost (marketed in the U.S., Canada and Europe by Allergan, under the trade name Lumigan) is a prostaglandin analog/prodrug used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. It reduces intraocular pressure (IOP) by increasing the outflow of aqueous fluid from the eyes.In December 2008, the indication to lengthen eyelashes was approved by the U.S. Food and Drug Administration (FDA); the cosmetic formulation of bimatoprost is sold as Latisse.In 2008-2011, at least three case series suggested that bimatoprost has the ability to reduce adipose (fat) tissue

Specification

Items

Specifications

Results

Appearance

White to almost white powder

White powder

Identification

HPLC retention time of sample complies with that of known sample

Complies

Specific rotation

[a]D20: +33.0°~+37.0°(C=1.0,CH3CN)

+36.0°

Water

≤1.0%

0.31%

Related substances

 

15R-Bimatoprost: ≤0.30%

Bimatoprostfree acid: ≤0.10%

5,6-trans-Bimatoprost: ≤0.50%

Any other single impurity: ≤0.10%

Total other impurities: ≤ 0.50%

Not detected

Not detected

0.07%

0.05%

0.18%

Residual solvents

 

Ter-Butylmethyl ether: ≤ 5000ppm

Ethanol: ≤5000ppm

N-Hexane: ≤ 290ppm

Ethyl acetate: ≤5000ppm

Not detected

Not detected

16.13ppm

18.92ppm

Purity

≥99.5%

99.82%

Usage  

  • 1) Treat of glaucoma

 

Bimatoprost is used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension.

It reduces intraocular pressure (IOP) by increasing the outflow of aqueous fluid from the eyes.

 

  •  2) For growth of lashes as cosmetic 

 It has also been used and prescribed off-label to lengthen eyelashes

 

  • 3)  For growth of hair

As the  FASEB Journal reporting, most of our client bought for the research of hair regrow. they estimate that this will be the next big use for bimatoprost around the world.

 

Share:

More Posts

ISRIB-A17 Custom Synthesis

ISRIB-A17 ISRIB-A17, which is nearly 10-fold more potent than ISRIB-A1 Technical Data for ISRIB M. Wt 451.34 Formula C22H24Cl2N2O4 Storage Store at +4°C Purity ≥99%

Male Pattern Hair Loss KX-826

What does KX-826 to do with Hairloss ? KX-826 is an androgen receptor (AR) antagonist and a potential first-in-class topical drug for the treatment of

Spermidine & anti-aging research

Spermidine VS Anti-Aging Spermidine is an aliphatic polyamine. Spermidine synthase (SPDS) catalyzes its formation from putrescine. Technical Data for Spermidine M. Wt 145.24600 Formula C7H19N3 Storage

Urolithin A on Anti-aging

Urolithin A exerts antiobesity effects through enhancing adipose tissue thermogenesis in mice Technical Data for Urolithin A M. Wt 228.2 Formula C13H8O4 Storage Store at

Send Us A Message