| Molecular Weight | 524.68 |
|---|---|
| Formula | C27H36N6O3S |
| CAS No. | 936091-26-8 |
| Storage | powder in solvent |
| Synonyms | SAR302503 |
| Smiles | CC1=CN=C(N=C1NC2=CC(=CC=C2)S(=O)(=O)NC(C)(C)C)NC3=CC=C(C=C3)OCCN4CCCC4 |
Pack 1G ,5G ,10G
TG101348 powder CAS 936091-26-8 Fedratinib
$245.00
Fedratinib (SAR302503, TG101348) is a selective inhibitor of JAK2 with IC50 of 3 nM in cell-free assays, 35- and 334-fold more selective for JAK2 versus JAK1 and JAK3. Fedratinib also inhibits FMS-like tyrosine kinase 3 (FLT3) and RET (c-RET) with IC50 of 15 nM and 48 nM, respectively. Fedratinib has potential antineoplastic activity.
