anti-arrhythmic GS458967 CAS 1262618-39-2 GS967


GS967 (GS458967) is a potent and selective inhibitor of late INa with anti-arrhythmic actions.

GS967 protects against seizures and prematurelethality in vivo. Chronic GS967 does not cause overt behavioraltoxicity or sedation in wild-type mice at theeffective anticonvulsant dose[2]. GS967 suppresses arrhythmogenicity evoked by ischemia, hypokalemia, and catecholamines in canine and porcine models

Molecular Weight 347.22
Formula C14H7F6N3O
CAS No. 1262618-39-2
Storage  powder
 in solvent
Synonyms GS458967
Smiles C1=CC(=CC=C1C2=CN3C(=NN=C3C(F)(F)F)C=C2)OC(F)(F)F
重量 0.25 kg



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