Where does Alpha-GPC come from?

alpha-GPC is produced by the chemical or enzymatic deacylation of phosphatidylcholine enriched soya phospholipids followed by chromatographic purification. Alpha-GPC may also be derived in small amounts from highly purified soy lecithin as well as from purified sunflower lecithin.

Alpha – GPC Powder or Alpha glycerylphosphorylcholine is a phospholipid metabolite and precursor to phosphatidylcholine and acetylcholine. … This soy-free Alpha GPC choline supplement helps improve your learning, memory, cognitive performance, and better brain function.

Is Alpha-GPC good for you?

Alpha-glycerylphosphorylcholine (Alpha-GPC) and caffeine supplementation have been shown to improve mental and physical performance. Alpha-GPC administration increases the release of the neurotransmitter acetylcholine and facilitates learning and memory.

According to the “cholinergic impairment hypothesis”, the pathogenesis of Alzheimer’s disease (memory, cognitive impairment, etc.) is closely related to the deficiency of the neurotransmitter acetylcholine, and if the level of acetylcholine in the brain is increased, the symptoms of Alzheimer’s disease can be significantly improved.

Synthetic Alpha GPC commonly have following spcification: 50% 85% 99% HPLC  

Technical Data for Alpha GPC

M. Wt257.22
FormulaC8H20NO6P
StorageStore at +4°C
Purity≥99% (HPLC)
CAS Number28319-77-9
EINECS248-962-2
Chemical nameCholine glycerophosphate
SmilesO=C(COC1=CC=C(Cl)C=C1)N[C@@H]2CC[C@@H](NC(COC3=CC=C(Cl)C=C3)=O)CC2

How to synthesis Alpha GPC ?

  • Soy lecithin was mixed with water to produce the mixture M1
  • Add phospholipase A1, phospholipase A2, calcium chloride and zinc chloride to the mixture M1 and react at a temperature of 30-45°C to produce the mixture M2
  • The mixture M2 was centrifuged and the supernatant was passed through a silica gel column and an ion exchange resin column to obtain the mixture M3
  • The mixture M3 was placed at a temperature of 5~0℃ for 40–60h to obtain crystals
  • The crystals were evaporated and concentrated to produce glycerophosphatidylcholine.

Share:

More Posts

Inhibitors Programs 2022

Custom Synthesis Programs 2022 Ponesimod CAS 854107-55-4 SB-334867 CAS 792173-99-0 AG-636 CAS 1623416-31-8 GDC-0077 CAS 2060571-02-8 BDP9066 CAS 2226507-04-4 Oliceridine CAS 1401031-39-7 GSK2881078 CAS 1539314-06-1

ISRIB-A17 Custom Synthesis

ISRIB-A17 ISRIB-A17, which is nearly 10-fold more potent than ISRIB-A1 Technical Data for ISRIB M. Wt 451.34 Formula C22H24Cl2N2O4 Storage Store at +4°C Purity ≥99%

Male Pattern Hair Loss KX-826

What does KX-826 to do with Hairloss ? KX-826 is an androgen receptor (AR) antagonist and a potential first-in-class topical drug for the treatment of

bimatoprost for eyelash growth?

Bimatoprost for eyelash growth Bimatoprost is a prostaglandin analog/prodrug used topically (as eye drops) to control the progression of glaucoma and in the management of

Send Us A Message