Noopept (N-phenyl-acetyl-L-prolylglycine ethyl ester) was constructed as a dipeptide analog of the standard cognition enhancer, piracetam. Our previous experiments have demonstrated the cognition restoring effect of noopept in several animal models of Alzheimer disease (AD). Noopept was also shown to prevent ionic disbalance, excitotoxicity, free radicals and pro-inflammatory cytokines accumulation, and neurotrophine deficit typical for different kinds of brain damages, including AD. In this study, we investigated the neuroprotective action of noopept on cellular model of AD, Aβ25–35-induced toxicity in PC12 cells and revealed the underlying mechanisms.
Technical Data for Noopept
M. Wt | 318.37 |
Formula | C17H22N2O4 |
Storage | Store at +4°C |
Purity | ≥99% (HPLC) |
CAS Number | 157115-85-0 |
Synonyms | ethyl 2-[[(2S)-1-(2-phenylacetyl)pyrrolidine-2-carbonyl]amino]acetate ,GVS-111,SGS 111 |
Solubility | Soluble in DMSO,DMF (25mg/ml) ethanol (20mg/ml) |
Appearance | A crystalline Solid |
Specification
TEST | SPECIFICATION | RESULTS |
Appearance | White crystalline powder | Conforms |
Assay | 99% min | 99.70% |
Melting point | 97℃~98℃ | 97℃~98℃ |
Heavy metals | NMT 10 ppm | Conforms |
Loss on drying | 0.50% Max | 0.35% |
Total Plate Count | 1000C fu/g Max | Conforms |
Yeast & Mold | 1000C fu/g Max | 50C fu/g Max |
E.Coli | Neagatitive | Conforms |
Salmonella | Neagatitive | Conforms |
Storage | Store in cool and dry place in a well-close container,Keep away from strong light and heat |
Conclusion | This product conforms to the Enterprise Standard. |
Noopept vs Piracetam
Noopept is often lumped together with Piracetam. While not a racetam, Noopept is structurally very similar to Piracetam, and the two nootropics have very similar effects.
Common benefits associated with both Piracetam and Noopept include:
- Improved memory function
- Enhanced learning
- Improved verbal fluency/fluidity
- Reduced inflammation and better brain health
The difference between Noopept and Piracetam is that Noopept is much more potent than Piracetam by weight. That means Noopept can deliver the same benefits as Piracetam with a significantly smaller dose. Generally speaking, you can expect to get the same effects as 3000mg of Piracetam from just 30mg of Noopept.