High purity Finasteride powder CAS 98319-26-7 99% HPLC 5α-reductase inhibitor DHT blocker for anti hair loss cosmetic and pharmaceutical research

High Purity Finasteride Powder CAS 98319-26-7 Anti Hair Loss DHT Blocker

High purity Finasteride powder CAS 98319-26-7 with 99% HPLC purity. Selective type II 5α-reductase inhibitor, effective DHT blocker for anti-hair loss and BPH research, factory bulk supply with full certificates.
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Finasteride CAS 98319-26-7 | Type II 5α-Reductase Inhibitor for Hair Loss & BPH | Nutrabiotech Chem

Finasteride CAS 98319-26-7
Type II 5α-Reductase Inhibitor (DHT Blocker)

Finasteride (CAS 98319-26-7) is a synthetic 4-azasteroid and a potent, selective inhibitor of the type II 5α-reductase enzyme. By lowering dihydrotestosterone (DHT), it is a benchmark research compound for androgenetic alopecia and benign prostatic hyperplasia (BPH). Formula C23H36N2O2, MW 372.55. Research / pharma grade with COA.

Finasteride5α-ReductaseDHT BlockerHair LossAndrogenetic AlopeciaBPHPropeciaAnti-Androgen
Request a Quote Technical Specs
372.55
MW (C23H36N2O2)
≥98%
Purity (HPLC)
Type II
5α-reductase

Molecular Information

Name: Finasteride
CAS: 98319-26-7
Formula: C23H36N2O2
MW: 372.55 g/mol
Class: 4-Azasteroid 5α-reductase inhibitor
Core: 4-Aza-5α-androst-1-ene-17β-carboxamide
Target: 5α-reductase (type II)
Activity: DHT suppression
MP: ~250-260 °C (reported)
Appearance: White to off-white crystalline powder
Synonyms: MK-906; Propecia; Proscar
Storage: -20°C, protect from light
98319-26-7
🧪
CAS Number
372.55
⚖️
Molecular Weight
5α-Reductase
🎯
Primary Activity
≥98%
✅
Purity

Product Technical Specifications

Complete physicochemical properties and QC parameters for Finasteride (CAS 98319-26-7)

📋 Physicochemical Properties

  • Product NameFinasteride
  • IUPAC NameN-(1,1-dimethylethyl)-3-oxo-4-aza-5α-androst-1-ene-17β-carboxamide
  • CAS Number98319-26-7
  • SynonymsMK-906; Propecia; Proscar
  • Molecular FormulaC23H36N2O2
  • Molecular Weight372.55 g/mol
  • SourceSynthetic 4-azasteroid
  • AppearanceWhite to off-white crystalline powder
  • Water SolubilityPractically insoluble
  • Organic SolubilityDMSO; ethanol; methanol
  • Melting Point~250-260 °C
  • Compound Class5α-reductase inhibitor (anti-androgen)
  • HS Code2937.29

🔬 Quality Control & Handling

  • Purity (HPLC)≥98%
  • FormCrystalline powder
  • Primary Target5α-reductase (type II)
  • Assay ReadoutDHT / androgen readouts
  • SelectivitySelective type II 5α-reductase
  • Storage Condition-20°C, sealed, protect from light
  • Solution StabilityDMSO stock stable at -20°C
  • ShippingRoom temp / cold chain
  • QC DocumentationCOA / HPLC / NMR / MS / MSDS
  • Pack Sizes100mg / 500mg / 1g / 5g / 10g
  • Stock StatusIn Stock
  • Use StatementResearch / formulation use; not for human clinical use

Key Molecular Targets & Pathway Nodes

Finasteride engages the androgen-metabolism machinery central to hair loss and prostatic research.

🧬 5α-Reductase (Type II) 🧬 Dihydrotestosterone (DHT) 🧬 Testosterone 🧪 Androgen pathway 💧 Scalp DHT 🧭 Hair follicle 🍃 Prostate (BPH) 🔬 Steroid SAR 🦲 Androgenetic alopecia 🧬 Anti-androgen

How Finasteride Works: Blocking DHT at the Source

Finasteride inhibits 5α-reductase, the enzyme that powers follicle miniaturization and prostatic androgenic growth.

1

Inhibition of Type II 5α-Reductase

Finasteride binds the type II isozyme of steroid 5α-reductase, preventing conversion of testosterone into the far more potent androgen dihydrotestosterone (DHT).

2

Reduction of DHT Levels

With the enzyme blocked, scalp and serum DHT fall substantially, relieving androgenic signaling in target tissues.

3

Follicular & Prostatic Response

Lower DHT reduces hair-follicle miniaturization (alopecia models) and prostatic androgenic stimulation (BPH models), restoring healthier phenotypes.

⚖️ Finasteride vs Comparators

  • Finasteride (this product)Selective type II 5α-reductase inhibitor
  • DutasterideDual type I + II 5α-reductase inhibitor
  • MinoxidilK⁺-channel vasodilator (topical)
  • Selective EdgeWell-characterized type II selectivity
  • Research NicheHair loss & BPH / androgen studies

♻️ Downstream Biological Consequences

  • Enzyme5α-reductase (II) blocked
  • AndrogenDHT markedly reduced
  • FollicleMiniaturization reversed
  • ScalpHair density readouts up
  • ProstateAndrogenic volume down (BPH)
  • ModelsAndrogen / alopecia pharmacology

Research & Formulation Applications

Finasteride is a benchmark anti-androgen for hair-loss, prostatic and endocrinology research.

🦲

Androgenetic Alopecia Research

Gold-standard reference compound for DHT-driven hair-follicle miniaturization models.

Hair Loss
🍃

BPH Models

Prostatic androgenic-stimulation and volume studies.

BPH
🧬

5α-Reductase Profiling

Benchmarks type II isozyme inhibition and steroid SAR.

5α-R
🧪

Androgen Pathway Studies

DHT, testosterone and AR-signaling assays.

Androgen
🌱

Hair-Regrowth Combos

Paired with minoxidil / aminexil in multi-target regimens.

Combo
🔬

Endocrinology Research

Steroid-metabolism and anti-androgen pharmacology.

Endo

Key Literature & Landmark Publications

Landmark clinical and preclinical work on finasteride, 5α-reductase and androgenetic alopecia.

Kaufman KD, et al. Finasteride in the treatment of men with androgenetic alopecia. J Am Acad Dermatol. 1998;39(4):578-589.
Landmark clinical reference
Gormley GJ, et al. The effect of finasteride in men with benign prostatic hyperplasia. N Engl J Med. 1992;327(17):1185-1191.
Landmark clinical reference
Review. 5α-reductase isozymes and androgen metabolism.
Landmark reference
Preclinical reports. Finasteride in follicle miniaturization models.
Landmark reference
Comparative studies. Finasteride vs dutasteride in alopecia and BPH.
Landmark reference

Available Sizes & Ordering

Research / pharma-grade Finasteride (CAS 98319-26-7) with full QC documentation; standard packs and bulk custom quantities supported.

TierPack SizeStock StatusSuitable ForLead Time
Standard100 mgIn StockReceptor / DHT assaysSame/next-day ship
Medium500 mgIn StockCell & binding studiesSame/next-day ship
Large1 gIn StockIn vivo modelsSame/next-day ship
Bulk5 gIn StockScreening & formulationQuote to confirm
Industrial10 g+Made to orderProcess developmentBatch delivery

💡 Reference sizes shown above; for exact pricing and availability please contact us for a quote. Bulk orders qualify for tiered discounts.

Frequently Asked Questions (FAQ)

What is finasteride and what is it researched for?
Finasteride (CAS 98319-26-7) is a synthetic 4-azasteroid and selective inhibitor of type II 5α-reductase, the enzyme that converts testosterone to dihydrotestosterone (DHT). It is studied in androgenetic alopecia and benign prostatic hyperplasia (BPH). Formula C23H36N2O2, MW 372.55.
How does finasteride work?
Finasteride binds and inhibits the type II 5α-reductase enzyme, lowering scalp and serum DHT levels. Reduced DHT relieves miniaturization of hair follicles (alopecia) and reduces prostatic androgenic stimulation (BPH).
What is the difference between finasteride and dutasteride?
Finasteride selectively inhibits the type II 5α-reductase isozyme; dutasteride inhibits both type I and type II isozymes and therefore suppresses DHT more completely. Both are studied for hair loss and BPH but differ in isoform coverage and pharmacokinetics.
How soluble is finasteride and how should it be prepared?
Finasteride is practically insoluble in water but soluble in DMSO, ethanol, methanol and other organic solvents. Prepare DMSO or ethanol stocks and store at -20°C protected from light.
Is finasteride a hormonal compound?
Finasteride is an anti-androgen that acts on the androgen (DHT) pathway rather than being a hormone itself. It is supplied for research and formulation use; not for human or clinical/injectable use without authorization.
Is QC documentation provided?
Every batch ships with a Certificate of Analysis (COA) including HPLC purity, NMR structural confirmation and MS data; MSDS/SDS and Certificates of Origin are available on request.

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Research / pharma-grade Finasteride (CAS 98319-26-7) — purity ≥98% HPLC, COA included
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